A tropical storm warning has been issued for coastal Ecuador and Venezuela as the Category 4 storm makes landfall on the east coast of the country.
The warning comes after the government announced on Monday it had received more than 50,000 applications for help with flooding.
The flood warnings have been issued in the coastal areas of Quito and Medellin and are expected to last into Tuesday.
“The coastal areas have experienced more than 20 years of inundation, with the loss of more than 100,000 homes and businesses,” the emergency declaration said.
It said that “several hundred” people have died as a result of flooding and landslides caused by the storm.
Hurricane warnings were also issued in northern Peru, Colombia, Colombia and Venezuela.
President Juan Manuel Santos announced a five-day extension to hurricane relief for coastal regions, but urged people to return to normal activities on Tuesday.
“It is a challenge for everyone,” he said.
“I am asking for patience and support from all citizens.
I ask for all of us to come together.”
He added that the government had deployed over 50,600 workers to assist people and infrastructure.